What Is SPRAVATO®?
SPRAVATO® contains esketamine and is administered as a prescription nasal spray in a supervised healthcare setting. It is used as part of specific treatment plans for certain adults with difficult-to-treat depression.
Uses, treatment information and how esketamine works in supervised clinical care.
SPRAVATO® contains esketamine and is administered as a prescription nasal spray in a supervised healthcare setting. It is used as part of specific treatment plans for certain adults with difficult-to-treat depression.
Esketamine acts on the brain’s glutamate system, including NMDA receptors. This mechanism is different from many traditional antidepressants and may produce effects more rapidly in some patients.
Treatment may be considered for eligible adults when a healthcare professional determines that esketamine is appropriate. A clinician evaluates the individual’s medical history, symptoms and previous treatments.
SPRAVATO® treatment is provided according to a structured clinical schedule. Patients are monitored by healthcare professionals during treatment, with follow-up appointments used to evaluate progress and ongoing needs.